At least two people have died in Manizales.
Speaking to BBC World Service, Angélica Ávila said she had been staying in a hotel in Manizales.
She said as the earthquake hit, cracks appeared in the walls.
“Everyone was screaming… I saw dust coming out of the neighbouring buildings, and bricks were falling off the walls,” she said.
Journalist and meteorologist Luis Felipe Molina, from Manizales, was at home when the earthquake struck – about 150km from the epicentre.
He explained that due to previous earthquakes, the city has “very strict seismic-resistant building regulations” – so his building was able to resist the impact.
“I have 450 books and only a few were left standing on the shelves. You could hear glass breaking and people screaming,” he told BBC Mundo.
“It was a terrible and terrifying experience.”
The country’s aviation authority has reported damage at several regional airports, including those in Pereira, Manizales, Quibdó, Armenia, Cartago and Buenaventura.
In the capital, Bogotá, trees and traffic lights shook violently, with reports of cracks in buildings but so far none of any serious damage to the city’s infrastructure.
Tremors were felt as far away as neighbouring Venezuela, Ecuador and Panama.
The quake comes less than two months after twin quakes devastated the north of Venezuela, killing more than 6,300 people.
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